Peran Karotenoid Sebagai Pencegahan Degenerasi Makula

Macular degeneration or often called Age-related Degeneration (AMD) is a degenerative disease that attacks the center of vision in retina, namely macula. In an effort to prevent progression AMD, consuming antioxidants has been shown inhibit AMD development process. Although currently there no definite number sufferers Indonesia, it estimated will continue increase. Carotenoids are one antioxidant compounds have macular degeneration. divided into several classes, which xanthophyll class. Lutein and zeaxanthin belong The content lutein body plasma reduce risk diseases such as AMD. This study aims determine role carotenoids prevention method used literature review form narrative review. Search journals textbooks through Google Scholar, PubMed, Science Direct, Research Gate, indexed by Scopus, ISSN, national international journals. were published last 5 years books 10 years. results analysis show carotenoid proven be able act reducing oxidative stress. quench free radicals, thereby preventing occurrence lipid peroxidation, formation also damage mediated exposure blue light. Consumption can expression VEGF (vascular endothelial growth factor) retina so increase VEGF. It concluded